Resumo
Phytochemicals have been reported to have direct
and/or indirect influence on the antibacterial potentials of
useful plants. The present study was aimed at determining the
phyto-components by traditional methods and GC-MS analysis
alongside testing the anti-bacterial activities of Desplatsia
dewevrei leaves and fruits. The maceration of 500 g of Desplatsia
dewevrei powder in methanol yielded 5.7 g of extract.
Qualitatively coumarins were found to be richly present in the
leaves while, quinones were most evidently present in the fruits
of Desplatsia dewevrei. Quantitative analyses show that the
phenolic and tannic acid contents of Desplatsia dewevrei may be
the chief compounds responsible for the antibacterial activity of
the plant. GC-MS results of Desplatsia dewevrei fruits and leaves
respectively showed Gas Chromatograms having 33 and 63
peaks representing different phyto-compounds. Of the 33 and 63
phyto-compounds, Cyclohexanepropanol, alpha.,2,2,6-tetrame
thyl and Farnesyl bromide were recurrent at different retention
time. Although Desplatsia dewevrei showed no zone of inhibition
for gram negative bacteria, its inhibitory effect on gram positive
bacteria is significant. In conclusion, D. dewevrei is a
phytochemical rich plant. However, a further study on the anti
bacterial effect of Desplatsia dewevrei using solvent extracts
other than methanol is recommended for future incorporation in
drug development.
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